Plane: Brno Airport provides connections to many countries in Europe and outside Europe. Many airlines transport every day a lot of tourists from around the world at Brno. Among the cheapest companies traveling to Brno are, for example, Ryanair and Wizz Air Bulgaria but also others such as Air or Smartwings have destination here. For more information visit http://www.brno-airport.cz/ flights
To get from the airport to the downtown easier, a convenient and fast option is to go by taxi. It has a rate of 398 CZK - 15 € or a little more.
Another comfortable option could be using the bus number 76 or 89 to the main train station by 25CZK - 1 €. More information: http://www.dpmb.cz/
Train: By train you can travel easily to Brno through the Czech Republic. There are also direct connections to Brno from Slovakia, Hungary, Germany and Austria. For this you can travel from the train station in Brno - Hlavní Nádraží.
Bus: Other connections from Europe to Brno there are available are for example, the bus line Eurolines. In many cases it is the cheapest way to travel long distances but is not advisable, since the trip takes time and also is tired.
Car: The transport car can be useful especially when you have to scroll through more cities and go with lots of luggage. Without problem you can get to Brno and then travel throughout the Czech Republic by car as there are highways practically from all over Europe.